Immunocompetence across autoimmune diseases

Objectives:

• Provide data on serious infections (SI) in ANCA-associated vasculitis (AAV) in the PEXIVAS study

Results:

• SI are common in AAV, occurring most often early after diagnosis or relapse, and are a significant cause of death, particularly early in follow-up.

Objective:

• Assess the frequency of thyroid disorders in nephrotic syndrome (NS).

Results:

• Thyroid dysfunction occurred in 2/3 of severe NS cases, with 26% of patients showing severe hypothyroidism requiring LT-4

Objective:

• Evaluate rituximab (RTX) efficacy in podocytopathies in a retrospective multicenter cohort.

Results:

• An 83% response rate to RTX was observed; maintenance therapy with RTX was the only factor linked to longer relapse-free survival